26/04/2017
Mónica Amorim, Principal Researcher at DBio/CESAM, published in Natures’ Scientific Reports “Variation-preserving normalization unveils blind spots in gene expression profiling.”
“(…) We have found that variation in gene expression is much larger than currently believed, and that it can be measured with available assays. Our results also explain, at least partially, the reproducibility problems encountered in transcriptomics studies. We expect that this improvement in detection will help efforts to realize the full potential of gene expression profiling, especially in analyses of cellular processes involving complex modulations of gene expression.”
For more information: http://www.nature.com/articles/srep42460